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Impact Santé: two Marseilles-based projects selected by Inserm

Inserm's Impact Santé program is designed to detect upstream research that could generate disruptive, high-impact innovations, and provide decisive support to the teams that take them up. Funded by France 2030, it has been allocated 30 million euros for its first year. Two projects from the Aix-Marseille site have been selected by Inserm in the fields of neuroscience and respiratory physiology.

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On May 2, 2024, the Impact Santé program was launched, coordinated by Inserm in conjunction with the entire biomedical research community. Find out more about the two projects funded by the Institut de Neurosciences des Systèmes (amU/Inserm) and the Institut de Neurobiologie de la Méditerranée (amU/Inserm).

Nautilus: towards less invasive, personalized brain medicine

Funded to the tune of 3 million euros, the Nautilus project is headed by Viktor Jirsa, CNRS Research Director at the Institut de Neurosciences des Systèmes. It is structured around the development of a technological platform capable of generating a digital double (or twin) of the brain of patients suffering from cerebral diseases, in order to assess their response to treatment by localized electrostimulation (currently used to treat epilepsy, depression, and Parkinson's disease).

The goal? To be able to predict the specific reaction of each patient's brain, fine-tune the intervention and minimize invasive surgical procedures. This innovative tool could thus revolutionize the treatment of brain diseases by enabling personalized, high-precision, non-invasive therapeutic intervention.

Aix-Marseille University (AMU) follows CNIL guidelines

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Discover the Nautilus project on video!

Voluntary control of breathing: a new neural network to discoverThe

"Voluntary control of breathing: diving into apnea" project is led by Clément Menuet, an Inserm researcher at the Mediterranean Neurobiology Institute. This "exploration" project focuses on identifying the neurons involved in the voluntary control of breathing, the only vital physiological function that can be voluntarily controlled. It has been funded to the tune of 150,000 euros.

By focusing on the neural networks involved in voluntary apnea, the project aims to identify potential new therapeutic targets for the treatment of respiratory and/or neurological disorders.

Aix-Marseille University (AMU) follows CNIL guidelines

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Discover the project on video!

Two other projects led by the Immunity and Cancer unit (Inserm/Institut Curie) and the Centre de recherche en épidémiologie et statistiques (Cress-Eren, Inserm/INRAE/Université Sorbonne Paris Nord/Université Paris-Cité) are also winners of this first wave of funding.